Smoking causes an inflammatory state in your body with release of various chemicals. These in turn alter the tubal lining promoting embryo receptivity for implantation. In addition, it decreases the movement of cilia and their number. This deciliation process along with abnormal signals produced by tobacco disrupts transport of the embryo.
Infections from previous surgery or miscarriage can induce tubal dysfunction. For instance, an infected appendix can lead to dysfunction or blockage of the right fallopian tube. Specifically, some of the infective organisms like Chlamydia trachomatis infection can alter the signal for embryo implantation.
Women over 35 years show more chances of ectopic gestation. It may be due to age-related tubal dysfunction and transportation or repeated interventions for infertility. Also, conception with assisted reproduction increases the risk for EP.
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