A blood transfusion entails getting red blood cell injections through a vein in order to restore normal amounts of healthy red blood cells and haemoglobin. Transfusions will be given every four months if you have moderate or severe thalassemia, and every two to four weeks if you have beta thalassemia major.
Iron chelation is the process of removing excess iron from your body. Blood transfusions have the potential to produce iron excess. Too much iron might harm your organs. If you require regular transfusions, you will be given iron chelation therapy (a tablet).
Folic acid supplements might assist your body in producing healthy blood cells.
The only way to cure thalassemia is to have a bone marrow and stem cell donation from a compatible related donor. Compatibility means that the donor and recipient have the same sorts of proteins on the surface of their cells, known as human leukocyte antigens (HLA).
Luspatercept is a three-week injectable that can help your body produce more red blood cells. It is approved for the treatment of transfusion-dependent beta thalassemia in the United States.
