Since blastocyst is an advanced stage embryo which has outgrown its fellow embryos it has certain advantages. It has a better survival rate and greater degree of implantation potential. Recognition by endometrium is better if an embryo is healthy and is in ready to be implanted stage.
The implantation rate for embryos transferred at day 5 was significantly higher than that for embryos transferred on day 3. Significantly fewer embryos were required for transfer at day 5 compared with day 3 embryo transfer. The high-order multiple gestation rate was significantly less with the day 5 (blastocyst) transfer than with the day 3 embryo transfer.
Blastocyst culture offers single embryo transfer and significantly reduce the risk of multiple pregnancy. Blastocyst culture can help to determine which embryos have the best chance of being able to implant. Extended culture allows the embryologist to identify which of a group of embryos have the best potential for implantation.
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