Women who will develop the endometrial hyperplasia produce too much estrogen and not enough progesterone hormones. These female hormones play vital roles in menstruation and pregnancy.
During ovulation, the estrogen hormone will thickens the endometrium, while progesterone will prepares the uterus for pregnancy. If conception doesn’t occurs, the progesterone levels will low. The progesterone drops and triggers the uterus to shed its lining as a menstrual period.
Women’s who have endometrial hyperplasia will make low level of progesterone. Consequently, the uterus doesn’t separate the endometrial lining. Instead of this the lining continues to grow and make as thicken.
Additionally, in obesity elevation of estrogen levels is seen. This fat tissue can change some of the hormones to estrogen. This is the how obesity contributes to elevated circulating levels of estrogen and increase the risk of endometrial hyperplasia.
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