Endometrial hyperplasia occurs when the lining of your uterus (endometrium) thickens. The endometrium is the lining of your uterus that sheds during your monthly cycle.
It is also the tissue from which a fetus develops during pregnancy. Endometrial hyperplasia, a kind of uterine cancer, can develop in some women and people assigned female at birth (AFAB).
uterine hyperplasia is classified by the types of cell alterations in your uterine lining. Some varieties of endometrial hyperplasia increase your risk of cancer significantly, whereas others do not.
Endometrial hyperplasia can be classified into the following types:
Simple or complex endometrial hyperplasia (without atypia): This form of endometrial hyperplasia has normal-looking cells that are unlikely to develop into cancer (“without atypia” meaning less likely to develop into cancer). This problem may improve without treatment, or your clinician may suggest hormone therapy.
Simple or complex atypical endometrial hyperplasia (with atypia): If the endometrial hyperplasia is “atypical” or “with atypia,” it is more likely to progress to cancer. Without treatment, your chances of developing endometrial or uterine cancer rise.
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