Sickle cell anaemia is a type of sickle cell disease, which is inherited. Sickle cell anaemia changes your red blood cells from round, flexible discs to rigid, sticky sickled cells.
Sickled cells prevent red blood cells from fulfilling their task of transporting oxygen throughout the body. Sickled cells also have a shorter lifespan than normal red blood cells.
Sickle cell anaemia is uncommon in the United States, affecting approximately 100,000 persons. It primarily affects persons with ancestors from places of the world where malaria is common and who inherit a gene that provides limited protection against anaemia. This gene is also responsible for sickle cell anaemia.
Babies with sickle cell anaemia may not exhibit symptoms for several months after birth. Symptoms of anaemia include excessive weariness or fussiness, excruciatingly swollen hands and feet, and jaundice.
Babies may also suffer spleen damage, which weakens their immune system and increases their susceptibility to bacterial infections.
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