Hyaluronate (HA) is a naturally occurring substance used as an additive to the liquid solution in which embryos are transferred into the womb. This is used as embryo glue in IVF cycle embryo transfer. Some studies show that adding HA to this transfer medium improves live birth rates. Due to its high concentration of hyaluronan it helps the embryo attach to endometrium. Its levels increase during implantation inside the uterine cavity. Subsequently, it helps in the successful attachment of the embryo to the uterine wall.
Preparation for embryo transfer requires transfer of the embryo into this special medium. The embryo is immersed into the medium for 10 to 15 mins before transfer. Higher concentration of hyaluronic acid helps the embryo for implantation.
The type of commercially available embryo culture medium used in IVF treatment has some restrictions in success. IVF success is not guaranteed using these available media. Hence IVF specialists continuously search for a better environment to improve the success of embryo implantation.
As these media undergo stringent therapeutic check before commercial use, there are no known risks linked. But, as with any medical treatment, you should discuss in detail for the best possible results.
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