Who are advised karyotyping before conception?

Who are advised karyotyping before conception?

Karyotyping can be advised to detect a variety of genetic disorders in specific clinical scenarios, few of them are:

• Premature ovarian failure – women attaining menopause early.
• Couples having recurrent miscarriages
• Couple facing problems in conceiving (infertility)
• Few sperms in the male partner
• Couple having history of delivering children with specific disorders
• Couple terminating pregnancy due to multiple congenital defects in the foetus.
• Advanced Maternal Age – Women over 35 years of age, those with a previous affected child, and those with a positive family history have a higher risk of chromosomal problems and miscarriage.
• Familial Associations with Specific Diseases
• Racial or Ethnic Associations to Specific Diseases
• Congenital bilateral absence of vas deferens in the male partner